Abstract

A Profile of Hypoxic Ischaemic Encephalopathy in Neonatal Intensive Care Unit, Gauhati Medical College and Hospital, Guwahati.

Author(s): Niladri Sekhar Bhunia, Niru Prabha Saharia

Objective: To study the incidence, risk factors and outcome of HIE in NICU of Gauhati Medical College and Hospital (GMCH). Design: Prospective study. Setting: Tertiary care Hospital. Participants: 228 term inborn babies who met the inclusion criteria were studied over a period of 12 months. Intervention: None Outcome measures: Incidence of HIE, Risk factors of HIE and Outcome among babies with HIE. Results: The incidence of HIE was 19.97/1000 term live births or 1.9%. The statistically significant antepartum, intrapartum risk factors were primigravida (p=0.0092), fetal distress (p=0.005) and prolonged labour (p=0.0003). When the antepartum and intrapartum risk factors were distributed in the three grades of HIE (HIE I, II, III) statistically significant risk factors were Spontaneous vaginal delivery/Assisted vaginal delivery (p=0.0177), fetal distress (p=0.0024) and prolonged labour (p=0.0264). Out of 228 babies with HIE 87(38.15%) were discharged, 71(31.14%) had expired and 70(30.71%) were taken away against medical advice by the attendants. There was no deaths in babies with HIE I, however 10(15.62%) babies with HIE II and 61(93.84%) babies with HIE III were expired. 59(60%) babies with HIE I was discharged, whereas 25(39%) babies with HIE II and only 3(4.6%) babies with HIE III were discharged. Conclusion: Incidence of HIE is very high .Some simple but important measures which will help to bring down this are: Early detection of high risk pregnancy and early referral to higher centre with proper facility, early detection of fetal distress, management of fetal distress, vigorous resuscitation at birth

Get the App