Author(s): Okafor C.N., Ofobruku S.A., Obi-Anike H.O., Agbaeze E.K.The purpose of this investigation is to determine the effects of human capital development on employees’ performance in Nigeria public hospital. The challenges of employees’ performance in Nigeria public hospitals have persisted, regardless of the government effort on human capital development. The situation is made worst in that much prior studies on human capital development in Nigeria only focused on other sectors, with limited literature on human capital development in Nigeria public hospitals. In order to have a comprehensive insight on the issue of employees’ performance in Federal Medical Hospital in Nigeria, this study utilised the survey approach. Data collected from survey questionnaire were analysed and tested using t-statistics generated from the model formulated for the three hypotheses. The data collected were analysed using the linear regression statistical technique. Results indicated that human capital development activities in Nigeria hospital can be used to optimize employees’ performance. In particular, the study found out that the lacks of articulate human capital development strategy geared towards filling identified skills, knowledge and attitude gap were responsible for the meagre employees’ performance in Nigeria hospitals. Therefore, the study recommends specifically that for human capital development process to be successful in Nigeria hospitals, there is need for prearranged and integrated employees’ development strategy. This should involve career support, training on-the-job and off-the-job training programs that are tailored towards filling the identified skills, knowledge and attitude gaps in Nigeria public hospitals.